Incorporated in 1993, Syngene International Ltd. is an innovation-focused global discovery, development, and manufacturing organization providing integrated scientific services to the pharmaceutical, biotechnology, nutrition, animal health, consumer goods, and specialty chemical industries around the world.

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Syngene’ s clientele includes world leaders such as Bristol-Myers Squibb, Baxter, Amgen, GSK, Merck KGaA, and Herbalife. Its innovative culture is driven by the passion of its 4240- strong team of scientists who work with clients from around the world to solve their scientific problems, improve R&D productivity, speed up time to market and lower the cost of innovation.

Position: Associate Scientist – Protein Biology

Department: Discovery Biology

Location: Bangalore, Karnataka, India

Job Description:

Job Purpose:

The incumbent will perform protein purification and characterization from various expression systems.

Key Responsibilities:

  • Independently perform protein purification from various expression systems (Mammalian, E. coli & Insect cell) and QC.
  • Prepare detailed reports for sharing with clients and attend telecons.
  • Improve lab efficiency and streamlines the operational processes to increase productivity.
  • Analyze operational problems, identify solutions, and implement corrective actions.
  • Guide and train research scientists in the team at various levels.
  • Follow environment, health, and safety (EHS) requirements at all times in the workplace ensuring individual and lab/plant safety
  • Attend training on environment, health, and safety (EHS) measures imparted company

Technical and Functional skills:

  • Expertise in routine protein purification with affinity, size exclusion, ion-exchange chromatography using AKTA FPLC systems (Unicorn software).
  • Expertise in protein purification of antibodies, affinity-tagged, secreted proteins as well as “problematic” proteins (low expression, poor solubility, intra-cellular expression, prone to aggregation).
  • Proficiency in protein extraction and solubilization methods, protein refolding and purification via affinity, hydrophobic interaction (HIC), ion exchange (IEX), size exclusion (SEC), and mixed-mode chromatography.
  • Expertise in the routine characterization of proteins including SDS-PAGE, SE-HPLC, and biophysical techniques.
  • Familiarity with mammalian and microbial protein expression is a plus

Behavioral Skills:

  • Be polite, assertive and collaborate well with colleagues
  • Take accountability and ownership for respective job function
  • Good verbal and written communication skills

Qualification: M.Sc/M.Tech/MS – Biotechnology/Biochemistry or relevant

Experience: 5-7 Years in Biotech/Pharma/R&D

Salary: Negotiable

Contact Details:

careers@syngeneintl.com

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